98 peer-reviewed articles · 4 book chapters · 2 editorials
Publications
Name in bold; underline marks first / co-first authorship;
an asterisk (*) marks co-corresponding authorship — following the conventions in the CV.
2026
★Torres, MDT; Wan, F; de la Fuente-Nunez, C. Deep learning reveals antimicrobial peptides within prions. Nature Microbiology, 2026.
Deb, R; Torres, MDT; Kabelka, I; Pribyl, J; Popper, M; Vreeker, E; Petrik, M; Maglia, G; de la Fuente-Nunez, C, Vacha, R. Computational design of antimicrobial peptide nanopores. Nature Chemical Biology, In press, 2026.
AI & deep learningAMP design & SARPeptide chemical modification
Yagati, AK; Torres, MDT; de la Fuente-Nunez, C. Colorimetric biosensors for pathogen detection: Toward accessible, scalable diagnostics. Cell Reports Physical Science, 103268, 2026.
★Torres, MDT; Zeng, Y; Wan, F; Maus, N; Gardner, J; de la Fuente-Nunez, C. A generative artificial intelligence approach for antibiotic optimization. Nature Machine Intelligence, v. 8, p. 841-856, 2026.
Kalimuthu, S; Torres, MDT; Leung, YY; de la Fuente-Nunez, C; Neelakantan, P. Design of a multimodal synthetic peptide antibiotic derived from human cathelicidin. Cell Biomaterials, 100452, 2026.
Gaglione, R; Schibeci, M; Piccolo, E; Culurciello, R; Zannella, C; Mensitieri, F; Del Piaz, F; Cafaro, V; De Filippis, A; Pizzo, E; Notomista, E; Torres, MDT; de la Fuente-Nunez, C; Arciello, A. Discovery of encrypted peptides in a human matrix metallopeptidase. JACS Au, v. 6, i. 1, 124-143, 2026.
2025
Maus, N; Kim, K; Zeng, Y; Jone, HT; Wan, F; Torres, MDT; de la Fuente-Nunez, C; Gardner, JR. Covering multiple objectives with a small set of solutions using Bayesian optimization. Advances in Neural Information Processing Systems, v. 38 (NeurIPS 2025), p. 75887-75930, 2025.
Jones, HJ; Maus, N; Ludan, JM; Huan, MZ; Liang, J; Torres, MDT; Liang, J; Ives, Z; Barash, Y; de la Fuente-Nunez, C; Gardner, JR; Yatskar, M. A dataset for distilling knowledge priors from literature for therapeutic design. Advances in Neural Information Processing Systems, v. 38 (NeurIPS 2025), 2025.
Beckman IV, RL; Martinez, B; Santiago, FZ; Echeverria, GN; Pinheiro, BV; Torres, MDT; Suits, L; Garcia, S; Wantuch, PL; de la Fuente-Nunez, C; Eswara, P; Rosen, DA; Fleeman, RM. Molecular response to non-lytic peptides triggers disruption of Klebsiella pneumoniae biofilm. Plos Pathogens, v. 21, i. 12, e1013437, 2025.
Levya, YC; Torres, MDT; Oliva, CA; de la Fuente-Nunez, C; Brizuela, CA. Key-cutting machine: Na evolutionary approach for protein and peptide design. Nature Machine Intelligence, v. 7, p. 1685-1697, 2025.
Bosso, A; Masino, A; Di Nardo, I; Zannella, C; Gaglione, R; Palumbo, I; Culurciello, R; De Filippis, A; Torres, MDT; de la Fuente-Nunez, C; Galdiero, M; Arciello, A; di Maro, A; Pizzo, E; Cafaro, V; Notomista, E. Exploring the antimicrobial and antiviral properties of encrypted peptides from human fibrinogen. International Journal of Molecular Sciences, v. 26, i. 18, 8914, 2025.
Torres, MDT; Chen, T; Wan, F; Chatterjee, P; de la Fuente-Nunez, C. Generative latent diffusion language modeling yields anti-infective synthetic peptides. Cell Biomaterials, 100183, 2025.
★Torres, MDT; Wan, F; de la Fuente-Nunez, C. Discovery of antibiotics in the archaeome using deep learning. Nature Microbiology, 10, 2153-2167, 2025. In Press.
Guan, C; Torres, MDT; Li, S; de la Fuente-Nunez, C. Venomics AI: a computational exploration of the global venoms for antibiotic discovery. Nature Communications, v. 16, 6446, 2025.
Amponnawarat, A; Torres, MDT; Krishnan, R; de la Fuente-Nunez, C; Ali, H. Synthetic peptides targeting an orphan GPCR display anti-infective potential. Cell Biomaterials, 100088, 2025.
Wan, F; Torres, MDT; Guan, C; de la Fuente-Nunez, C. Accelerating antibiotic discovery through computational genome and proteome mining. Nature Protocols, v. 20, p. 2685-2697, 2025.
Ageitos, L; Boaro, A; Cesaro, A; Torres, MDT; Broset, E; de la Fuente-Nunez, C. Frog-derived synthetic peptides act as antimicrobials with anti-infective activity. Trends in Biotechnology, v. 43, i. 7, p. 1642-1667, 2025.
2024
Torres, MDT; Cesaro, A; de la Fuente-Nunez, C. Encrypted peptides from the human proteome target infections through antimicrobial and immunomodulatory properties. Trends in Biotechnology, v. 43, i. 1, p. 184-205, 2024.
★Torres, MDT; Brooks, E; Cesaro, A; Sberro, H; Nicolaou, C; Bhatt, AS; de la Fuente-Nunez, C. Human gut metagenomic mining reveals an untapped source of peptide antibiotics. Cell, v. 187, i. 19, p. 5453-5467.E152024.
Deb, R; Torres, MDT; Boudny, M; Koberska, M; Cappiello, F; Petrik, M; Bendova, KD; Drabinova, M; Hanackova, A; Jeannot, K; Popper, M; Mangoni, ML; Novotna, GB; Mraz, M, de la Fuente-Nunez, C; Vacha, R. Computational design of barrel-stave pore-forming peptides with potent antimicrobial and anticancer activities. Journal of Medicinal Chemistry, v. 67, i. 16, p. 14040-14061, 2024.
★Santos-Junior, CD; Torres, MDT; Duas, Y; del Rio, AR; Schmidt, TSB; Chong, H; Fullam, A; Kuhn, M; Zhu, C; Houseman, A; Somborski, J; Vines, A; Zhao, XM; Bork, P; Huerta-Cepas, J; de la Fuente-Nunez, C, Coelho, LP. Computational exploration of the global microbiome for antibiotic discovery. Cell, v. 187, i. 14, p. 3761-3778.E16, 2024.
★Wan, F; Torres, MDT; Peng, J, de la Fuente-Nunez, C. Molecular de-extinction of antibiotics enabled by deep learning. Nature Biomedical Engineering, v.8, i. 7, p. 854-871, 2024.
De los Santos, L; Sheiber, J; DeBarro, C; Keener, J; Torres, MDT; de la Fuente-Nunez, C; Brodbelt, JS; Fleeman, RM. Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms. Cell Reports Physical Sciences, v. 5, i. 3, 101869, 2024.
Reffuveille, F; Dghoughi, T; Colin, M; Torres, MDT; de la Fuente-Nunez, C. Antibiofilm approaches as a new paradigm for treating infections. Progress in Biomedical Engineering, v. 6, i. 2, 023001, 2024.
Araujo, WR; Lukas, H; Torres, MDT; Gao, W; de la Fuente-Nunez, C. Low-cost Biosensors Technologies for Rapid Detection of COVID-19 and Future Pandemics. ACS Nano, v. 18, i. 3, p. 1757-1777, 2024.
Silva, AF; Torres, MDT; Silva, LS; Alves, FL; Pinheiro, AAS; Miranda, A; de la Fuente-Nunez, C; Oliveira, VX Jr. Synthetic angiotensin II derivatives with anti-infective efficacy in a preclinical murine model of severe cerebral malaria. Scientific Reports, v. 14, 4682, 2024.
2023
Nazarian-Firouzabadi, F; Torres, MDT; de la Fuente-Nunez, C. Recombinant production of antimicrobial peptides in plants. Biotechnology Advances, v. 71, 108296, 2023.
Chiloeches, A; Zágora, J; Plachá, D; Torres, MDT; de la Fuente-Nunez, C; Lopez-Fabal, F; Gil Romero, Y; Fernández-García, R; Fernández-García, M; Echeverria, C; Munoz-Bonilla, A. Synergistic Combination of Antimicrobial peptides and Cationic Polytaconates in Multifunctional PLA Fibers. ACS Applied Bio Materials, v. 6, i. 11, p. 4805-4813, 2023.
Cesaro, A; Bagheri, M; Torres, MDT; Wan, F; de la Fuente-Nunez, C. Deep learning to accelerate antibiotic Discovery. Expert Opinion on Drug Discovery, v. 18, i. 11, p. 1245-1257, 2023.
Maasch, JRMA; Torres, MDT; Melo, MCR; de la Fuente-Nunez, C. Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning. Cell Host Microbe, v. 31, i. 8, p. 1260-1274.E6, 2023.
Averbeck, S; Xu, D; Murphy, B; Shevchuk, K; Shankar, S; Anayee, M; Torres, MDT; Beauchamp, M; de la Fuente-Nunez, C; Gogotsi, Y; Vitale, F. Stability of Ti3C2Tx MXene Films and Devices under Clinical Sterilization Processes. ACS Nano, v. 17, i. 10, p. 9442-9454, 2023.
Pedron, CN; Torres, MDT; Oliveira, CS; Silva, AF; Andrade, GP; Wang, Y; Pinhal, MAS; Cerchiaro, G; Silva Jr, PI; Silva, FD; Radhakrishnan, R; de la Fuente-Nunez, C; Oliveira Jr, VX. Molecular hybridization strategy for tuning peptide biological function. Communications Biology, v. 6, 1067, 2023.
Boaro, A; Ageitos, L; Torres, MDT; Blasco, EB; Oztekin, S; de la Fuente-Nunez, C. Rational design of anti-infective synthetic peptides from wasp venom. Cell Reports Physical Sciences, v. 4, i. 7, 101459, 2023.
Lima, LF; Ferreira, AL; Awasthi, S; Torres, MDT; Friedman, HM; Cohen, G; Araujo, WR; de la Fuente-Nunez, C. Rapid and accurate detection of Herpes Simplex Virus type 2 using a low-cost electrochemical biosensor. Cell Reports Physical Sciences, v. 4, i. 9, 101513, 2023.
2022
Ageitos, L; Torres, MDT; de la Fuente-Nunez, C. Biologically active peptides from venoms: Applications in antibiotic resistance, cancer and beyond. International Journal of Molecular Sciences, v. 23, i. 23, 15437, 2022.
Torres, MDT; de la Fuente-Nunez, C. Molecular tools for microbiome engineering. Current Opinion in Structural Biology, v. 76, 102415, 2022.
Cardoso, MH; Chan, LY; Candido, ES; Torres, MDT; Oshiro, KGN; Silva, IC; Gonçalves, S; Buccini, DF; Lu, TK; Santos, NC; de la Fuente-Nunez, C; Craik, DJ; Franco, OL. An asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. Chemical Science, v. 13, p. 9410-9424, 2022.
Daniell, H; Nair, SK; Guan, H; Guo, Y; Kulchar, RJ; Torres, MDT; Shahed-Al-Mahmud, M; Liu, YM; Graham-Wootenand, J; Zhou, W; Wang, P; Mante, F; de la Fuente-Nunez, C; Ma, C; Ricciardi, R; Collman, RG; Wolff, MS. Debulking different Corona (SARS-COV-2 delta, omicron, OC43) and Influenza (H1N1, H3N2) virus strains by plant viral trap proteins in chewing gums to decrease infection and transmission. Biomaterials, v. 228, p. 121671, 2022.
Arque, X.; Torres, MDT; Patino, T; Boaro, A; Sanchez, S, de la Fuente-Nunez, C. Autonomous treatment of bacterial infections in vivo using antimicrobial micro-and nanomachines. ACS Nano, v. 16, i. 5, p. 7547-7558, 2022.
Torres, MDT; Lima, LF; Lopes, AF; Araujo, WR; Callahan, P; Davila, A; Abella, BS; de la Fuente-Nunez, C. Detection of SARS-CoV-2 with RAPID: a prospective cohort study. iScience, v. 25, i. 4, 104055, 2022.
Cesaro, A; Torres, MDT; Galione, R; Dell’Olmo, E; Di Girolamo, R; Bosso, A; Pizzo, E; Haagsman, HP; Veldhuizen, EJA; de la Fuente-Nunez, C; Arciello, A. Synthetic antibiotic derived from sequences encrypted in human plasma apolipoprotein B. ACS Nano, v. 16, i. 2, p. 1880-1895, 2022.
★Torres, MDT; Melo, MCR; Flowers, L; Crescenzi, O; Notomista, E; de la Fuente-Nunez, C. Mining for encrypted peptide antibiotics in the human proteome. Nature Biomedical Engineering, v. 6, i. 1, p. 67-75, 2022.
2021
Lopes, AF; Lima, LF; Torres, MDT; Araujo, WR; de la Fuente-Nunez, C. COLOR: a low-cost optodiagnostic for minute-timescale detection of SARS-CoV-2. ACS Nano, v. 15, i. 11, p. 17453-17462, 2021.
Oliveira, CS; Torres, MDT; Pedron, CN; Andrade, VB; Andrade, GP; Cerchiaro, G; Silva Jr, PI; Silva, FD; de la Fuente-Nunez, C; Oliveira Jr, VX. Synthetic peptide derived from scorpion venom displays minimal toxicity and anti-infective activity in mice. ACS Infectious Diseases, v. 7, i. 9, p. 2736-2745, 2021.
Lima, LF; Lopes, AF; Torres, MDT; Araujo, WR; de la Fuente-Nunez, C. Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes. Proceedings of the National Academy of Sciences of the United States of America, v. 118, i. 30, e21067224118, 2021.
Meurer, M; O’Neil, DA; Lovie, E; Simpson, L; Torres, MDT; de la Fuente-Nunez, C; Angeles-Boza, AM; Kleinsorgen, C; Mercer, DK; von Kockritz-Blickwede, M. Antimicrobial susceptibility testing of antimicrobial peptides requires new and standardized testing structures. ACS Infectious Diseases, v. 7, i. 8, p. 2205-2208, 2021.
Torres, MDT; Araujo, WR; Lima, LF; Lopes, AF; de la Fuente-Nunez, C. Low-cost biosensor for rapid detection of SARS-CoV-2 at the point-of-care. Matter, v. 4, p. 1-14, 2021.
Palmer, N; Maasch, JRMA; Torres, MDT; de la Fuente-Nunez, C. Molecular dynamics for antimicrobial peptide discovery. Infection & Immunity, v. 89, i. 4, 2021.
Torres, MDT; Cao, J; Franco, OL; Lu, TK; de la Fuente-Nunez, C. Synthetic biology and computer-based frameworks for antimicrobial peptide discovery. ACS Nano, v. 15, i. 2, p. 2143-2164, 2021.
Silveira, GGOS; Torres, MDT; Ribeiro, CFA; Carvalho, CME; de la Fuente-Nunez, C; Franco, OL; Cardoso, MH. Anti-biofilm peptides: Relevant preclinical animal infection models and translational potential. ACS Pharmacology & Translational Science, v. 4, i. 1, 55-73, 2021.
Pedron, CN; Silva, AF; Torres, MDT; Oliveira, CS; Andrade, GP; Cerchiaro, G; Pinhal, MAS; de la Fuente-Nunez, C; Oliveira Jr, VX. Net charge tuning modulates the antiplasmodial and anticancer properties of peptides derived from scorpion venom. Journal of Peptide Science, v. 27, i. 4, e3296, 2021.
Torres, MDT; Voskian, S; Brown, P; Liu, A; Lu, TK; Hatton, TA; de la Fuente-Nunez, C. Ionic Liquid-Based Ionogel Coatings for Pathogen Eradication. ACS Nano, v. 15, i. 1, p. 966-978, 2021.
2020
Boaro, A; Ageitos, L; Torres, MDT; Bartoloni, FH; de la Fuente-Nunez, C. Light-emitting probes for labeling peptide. Cell Reports Physical Science, v. 1, i. 12, 100257, 2020.
Ahmed, A; Risner, K; Kortchak, S; Nakovic, A; Torres, MDT; de la Fuente-Nunez, C; Lu, TK; Bhalla, N; Narayanan, A. Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response. Scientific Reports, v. 10, 21491, 2020.
★Silva, ON; Torres, MDT; Cao, J; Alves, ESF; Rodrigues, LV; Resende, JM; Lião, LM; Porto, WF; Fensterseifer, ICM; Lu, TK; Franco, OL; de la Fuente-Nunez, C. Repurposing a peptide toxin from wasp venom into anti-infectives with dual antimicrobial and immunomodulatory properties. Proceedings of the National Academy of Sciences of the United States of America, v. 117, i. 43, p. 26936-26945, 2020.
Pedron, CN; Freire, KA; Torres, MDT; Lima, DB; Monteiro, ML; Menezes, RRPB; Martins, AMC; Oliveira Jr, VX. Arg-substituted VmCT1 analogs reveals promising candidate for the development of new antichagasic agent. Parasitology, v. 147, i. 14, p. 1810-1818, 2020.
Echeverria, C; Torres, MDT; Fernandez-Garcia, M; de la Fuente-Nunez, C; Munoz-Bonilla, A. Physical methods for controlling bacterial colonization on polymer surfaces. Biotechnology Advances, v. 43, 107586, 2020.
Mercer, DK; Torres, MDT; Duay, SS; Lovie, E; Simpson, L; von Köckritz-Blickwede, M; de la Fuente-Nunez, C; O'Neil, DA; Angeles-Boza, AM. Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy. Frontiers in Cellular and Infection Microbiology, 10:326, 2020.
Freire, KA; Torres, MDT; Lima, DB; Monteiro, ML; Menezes, RRPPB; Martins, AMC; Oliveira Jr., VX. Wasp venom peptide as a new antichagasic agent. Toxicon, v. 181, p. 71-78, 2020.
Torres, MDT; Silva, AF; Andrade, GP; Pedron, CN; Cerchiaro, G; Ribeiro, AO; Oliveira Jr, VX; de la Fuente-Nunez, C. The wasp venom antimicrobial peptide Polybia-CP and its synthetic derivatives display antiplasmodial and anticancer properties. Bioengineering & Translational Medicine, e10167, 2020.
Silva, RF; Paixao, TRLC; Torres, MDT; Araujo, WR. Simple and inexpensive electrochemical paper-based analytical device for sensitive detection of Pseudomonas aeruginosa. Sensors and Actuators B: Chemical, 127669, 2020.
Cruz, GF; Araujo, I; Torres, MDT; de la Fuente-Nunez, C; Oliveira Jr, VX, Ambrosio, FN; Lombello, CB; Almeida, DV; Silva, FD; Garcia W. Photochemically-generated silver chloride nanoparticles stabilized by a peptide inhibitor of cell division and its antimicrobial properties. Journal of Inorganic and Organometallic Polymers and Materials, v. 30, i. 1, p. 1-11, 2020.
2019
Torres, MDT; de la Fuente-Nunez, C. Reprogramming biological peptides to combat infectious diseases. Chemical Communications, v. 55, i. 100, p. 15020-15032, 2019.
Yehl, K; Lemire, S; Yang, AC; Ando, H; Mimee, M; Torres, MDT; de la Fuente-Nunez, C; Lu, TK. Engineering phage host-range and suppressing bacterial resistance through phage tail fiber mutagenesis. Cell, v. 179, i. 2, p. 459-469, 2019.
Agbale, CM; Sarfo, JK; Galyuon, IK; Juliano, SA; Silva, GGO, Buccini, DF; Cardoso, MH; Torres, MDT; Angeles-Boza, AM; de la Fuente-Nunez, C; Franco, OL. Antimicrobial and antibiofilm activities of helical antimicrobial peptide sequences incorporating metal-binding motifs. Biochemistry, v. 58, i. 36, p. 3802-3812, 2019.
Oshiro, KGN; Cândido, ES; Chan, LY; Torres, MDT; Monges, BED; Rodrigues, SG; Porto, WF; Ribeiro, SM; Henriques, ST; Lu, TK; de la Fuente-Nunez, C; Craik, DJ; Franco, OL; Cardoso, MH. Computer-aided design of mastoparan-like peptides enables the generation of non-toxic variants with extended antibacterial properties. Journal of Medicinal Chemistry, v. 62, i. 17, p. 8140-8151, 2019.
Pedron, CP; Oliveira, CS; Silva, AF; Andrade, GP; Pinhal, MAS; Cerchiaro, G; Silva Jr, PI; Silva, FD; Torres, MDT*; Oliveira Jr, VX*. The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1. European Journal of Pharmaceutical Sciences, v. 136, 104952, 2019.
Pedron, CP; Araujo, I; Silva Jr, PI; Silva, FD; Torres, MDT*; Oliveira Jr, VX*. Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens. Bioorganic Chemistry, v. 90, 103038, 2019.
Cândido, ES; Cardoso, MH; Chan, LY; Torres, MDT; Oshiro, KGN; Porto, WF; Ribeiro, SM; Haney, EF; Hancock, REW; Lu, TK; de la Fuente-Nunez, C; Craik, DJ; Franco, OL. A short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential. ACS Infectious Diseases, v. 5, i. 7, p. 1081-1086, 2019.
Fensterseifer, ICM; Felício, MR; Alves, ESF; Cardoso, MH; Torres, MDT; Matos, CO; Silva, ON; Lu, TK; Freire, MV; Neves, NC; Gonçalves, S; Lião, LM; Santos, NC; Porto, WF; de la Fuente-Nunez, C; Franco, OL. Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria. Biochimica et Biophysica Acta (BBA) – Biomembranes, v. 1861, i. 7, p. 1375-1387, 2019.
Torres, MDT; de la Fuente-Nunez, C. Toward computer-made artificial antibiotics. Current Opinion in Microbiology, v. 51, p. 30-38, 2019.
Torres, MDT; Sothiselvam, S; Lu, TK; de la Fuente-Nunez, C. Peptide design principles for antimicrobial applications. Journal of Molecular Biology, v. 431, i. 18, p. 3547-3567, 2019.
2018
Torres, MDT; Pedron, CN; Higashikuni, Y; Kramer, RM; Cardoso, MH; Oshiro, KGN; Franco, OL; Silva Jr, PI; Silva, FD; Oliveira Jr, VX; Lu, TK; de la Fuente-Nunez, C. Structure-function-guided exploration of the antimicrobial peptide Polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. Communications Biology, v. 1, 221, 2018.
Cardoso, MH; Candido, E; Chan, L; Torres, MDT; Oshiro, K; Rezende, S; Porto, WF; Lu, TK; de la Fuente-Nunez, C; Craik, DJ; Franco, OL. A computationally designed peptide derived from E. coli as a potential drug template for antibacterial and antibiofilm therapies. ACS Infectious Diseases, v. 4, 12, p. 1727-1736, 2018.
Boase, N; Torres, MDT; Fletcher, N; de la Fuente-Nunez, C; Fairfull-Smith, K. Polynitroxide copolymers to reduce biofilm fouling on surfaces. Polymer Chemistry, v.9, p. 5308-5318, 2018.
Pane, K; Cafaro, V; Avitable, A.; Torres, MDT; Vollaro, A; De Gregorio, E; Catania, MR; Di Maro, A; Bossa, A; Gallo, G; Zanfardino, A; Varcamonti, M; Pizzo, E; Di Donato, A; Lu, TK; de la Fuente-Nunez, C; Notomista, E. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational–Experimental Platform. ACS Synthetic Biology, v. 7, i. 9, p. 2105-2115, 2018.
Porto, WF; Irazazabal, L; Alves, ESF; Ribeiro, SM; Matos, CO; Pires, AS; Fensterseifer, ICM; Miranda, VJ; Haney, EF; Humbolt, V; Torres, MDT; Hancock, REW; Liao, LM; Ladram, A; Lu, TK; de la Fuente-Nunez, C; Franco, OL. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications, v. 9, p. 1490, 2018.
Pizzo, E; Pane, K; Bosso, A; Landi, N; Ragucci, S; Russo, R; Gaglione, R; Torres, MDT; de la Fuente-Nunez, C; Arciello, A; Di Donato, A; Notomista, E; Di Maro, A. Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities. Biochimica et Biophysica Acta (BBA)-Biomembranes, v. 1860, p. 1425-1435, 2018.
Torres, MDT; Andrade, GP; Sato, RH; Pedron, CN; Manieri, TM; Cerchiaro, G; Ribeiro, AO; de la Fuente-Nunez, C; Oliveira, VX Jr. Natural and redesigned wasp venom peptides with selective antitumoral activity. Beilstein Journal of Organic Chemistry, v. 14, p. 1693-1703, 2018.
Torres, MDT; Silva, AF; Pedron, CN; Capurro, ML; de la Fuente-Nunez, C; Oliveira, VX Jr. Peptide Design Enables Reengineering of an Inactive Wasp Venom Peptide into Synthetic Antiplasmodial Agents. ChemistrySelect, v. 3, p. 5859-5863, 2018.
Cao, J; de la Fuente-Nunez, C; Ou, RW; Torres, MDT; Pande, SG; Sinskey, AJ; Lu, TK. Yeast-based synthetic biology platform for antimicrobial peptide production. ACS Synthetic Biology, v. 7, i. 3, p. 896-902, 2018.
Pedron, CN; Andrade, GP; Sato, RH; Torres, MDT; Cerchiaro, G; Ribeiro, AO; Oliveira Jr, VX. Anticancer activity of VmCT1 analogs against MCF-7 cells. Chemical Biology & Drug Design, v. 91, p. 588-596, 2018.
de la Fuente-Nunez, C; Brown, P; Torres, MDT; Cao, J; Lu, TK. Magnetic surfactant ionic liquids and polymers with tetrahaloferrate (III) anions as antimicrobial agents with low cytotoxicity. Colloid and Interface Science Communications, v. 22, p. 11-13, 2018.
2017
Pedron, CN; Torres, MDT; Lima, JAS; Silva, PI; Silva, FD; Oliveira Jr, VX. Novel designed VmCT1 analogs with increased antimicrobial activity. European Journal of Medicinal Chemistry, v. 126, p. 456-463, 2017.
Torres, MDT; Pedron, CN; Araújo, I; Silva, PI; Silva, FD; Oliveira Jr, VX. Decoralin Analogs with Increased Resistance to Degradation and Lower Hemolytic Activity. ChemistrySelect, v. 2, p. 18-23, 2017.
de la Fuente-Nunez, C; Torres, MDT; Mojica, FJM; Lu, TK. Next-generation precision antimicrobials: towards personalized treatment of infectious diseases. Current Opinion in Microbiology, v. 37, p. 95-102, 2017.
Silva, AF; Torres, MDT; Silva, LS; Alves, FL; Pinheiro, AAS; Miranda, A; Capurro, ML; de la Fuente-Nunez, C; Oliveira Jr, VX. Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction. Scientific Reports, v. 7, p. 14326, 2017.
Torres, MDT; Pedron, CN; Lima, JAS; Silva, PI; Silva, FD; Oliveira Jr, VX. Antimicrobial activity of leucine-substituted decoralin analogs with lower hemolytic activity. Journal of Peptide Science, v. 23, p. 818-823, 2017.
2016
Torres, MDT; Silva, AF; Alves, FL; Capurro, ML; Miranda, A; Cordeiro, RM; Oliveira Jr, VX. Evidences for the action mechanism of angiotensin II and its analogs on Plasmodium sporozoite membranes. Journal of Peptide Science, v. 22, p. 132-142, 2016.
2015
Torres, MDT; Silva, AF; Silva, LS; Pinheiro, AAS; Oliveira Jr, VX. Angiotensin II restricted analogs with biological activity in the erythrocytic cycle of Plasmodium falciparum. Journal of Peptide Science, v. 21, p. 24-28, 2015.
Torres, MDT; Silva, AF; Alves, FL; Capurro, ML; Miranda, A; Oliveira Jr, VX. Highly Potential Antiplasmodial Restricted Peptides. Chemical Biology & Drug Design, v. 85, p. 163-171, 2015.
Silva, AF; Silva, LS; Alves, FL; Torres, MDT; Pinheiro, AAS; Miranda, A; Capurro, ML; Oliveira Jr, VX. Effects of the angiotensin II Ala-scan analogs in erythrocytic cycle of Plasmodium falciparum (in vitro) and Plasmodium gallinaceum (ex vivo). Experimental Parasitology, v. 153, p. 1-7, 2015.
Silva, AF; Torres, MDT; Silva, LS; Alves, FL; Pinheiro, AAS; Miranda, A; Capurro, ML; Oliveira Jr, VX. New linear antiplasmodial peptides related to angiotensin II. Malaria Journal, v. 14, p. 1-10, 2015.
Silva, AF; Alves, FL; Pedron, CN; Torres, MDT; Silva, LS; Pinheiro, AAS; Miranda, A; Oliveira Jr, VX. Anti-plasmodial activity of Bradykinin and analogs. Bioorganic & Medicinal Chemistry Letters, v. 25, p. 3311-3313, 2015.
2014
Silva, AF; Bastos, EL; Torres, MDT; Silva, ALC; Ioshino, RS; Capurro, ML; Alves, FL; Miranda, A; Vieira, RFF; Oliveira Jr, VX. Antiplasmodial activity study of angiotensin II via Ala scan analogs. Journal of Peptide Science, v. 20, p. 640-648, 2014.
Torres, MDT; Silva, AF; Alves, FL; Capurro, ML; Miranda, A; Oliveira Jr, VX. The Importance of Ring Size and Position for the Antiplasmodial Activity of Angiotensin II Restricted Analogs. International Journal of Peptide Research and Therapeutics, v. 20, p. 277-287, 2014.
Ferreira, LHR; Silva, AF; Torres, MDT; Pedron, CN; Capurro, ML; Alves, FL; Miranda, A; Oliveira Jr, VX. Effects of Amino Acid Deletion on the Antiplasmodial Activity of Angiotensin II. International Journal of Peptide Research and Therapeutics, v. 20, p. 553-564, 2014.
2013
Chamlian, M; Bastos, EL; Maciel, C; Capurro, ML; Miranda, A; Silva, AF; Torres, MDT; Oliveira Jr, VX. A study of the anti-plasmodium activity of angiotensin II analogs. Journal of Peptide Science, v. 19, p. 575-580, 2013.
Book chapters (4)
Cesaro, A; Torres, MDT; de la Fuente-Nunez, C. Methods for the design and characterization of peptide antibiotics. Methods in Enzymology, v. 663, p. 303-326, 2022.
Silva, AF; Alves, FL; Torres, MDT; Pedron, CN; Oliveira Jr, VX. Peptídeos: Jogadores que atuam em todos os campos da vida. In: Janaína de Souza Garcia. (Org.). Contém Química. 1ed. Santo André: Editora UFABC, 2016, v. 2, p. 189-200.
AMP design & SAR
Torres, MDT; Pedron, CN; Silva, AF; Alves, FL; Oliveira Jr, VX. Antimicrobianos: Os exterminadores do presente. In: Janaína de Souza Garcia. (Org.). Contém Química. 1ed. Santo André: Editora UFABC, 2016, v. 2, p. 143-156.
AMP design & SAR
Torres, MDT; Silva, AF; Vieira, RFF; Quaglio, LM; Oliveira Jr, VX. Interações de Fármacos em Sistemas Biológicos. In: Wendel Andrade Alves. (Org.). Química Supramolecular e Nanotecnologia. 1ed., 2014, v. 1, p. 227-248.
AMP design & SAR
Editorials (2)
Lopez, FC; Torres, MDT; Brandelli, A; Meira, S. Special Issue: Potential applications of antimicrobial Peptides. Frontiers in Bioengineering & Biotechnology. 2022.
AMP design & SAR
Torres, MDT; de la Fuente-Nunez, C; Farres, XV; Rabanal, F. Special Issue: Antimicrobial peptides, potent weapons to fight multidrug-resistant bacteria. Frontiers in Cellular and Infection Microbiology. 2021.
AMP design & SAR